Paclitaxel resistance by random mutagenesis of α-tubulin
نویسندگان
چکیده
منابع مشابه
Paclitaxel resistance by random mutagenesis of α-tubulin.
Many mammalian β-tubulin mutations that confer paclitaxel resistance have been characterized, but little is currently known about the role of α-tubulin mutations in drug resistance. Previous studies using two-dimensional gel electrophoresis showed that α-tubulin mutations occur with a frequency equal to β-tubulin mutations among CHO cells selected for resistance to paclitaxel but the identities...
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ژورنال
عنوان ژورنال: Cytoskeleton
سال: 2013
ISSN: 1949-3584
DOI: 10.1002/cm.21154